Do not use a household spoon because you may not get the correct dose. What Are the Side Effects of Promethazine DM? Improper use of this medication (abuse) may result in serious harm (including brain damage, seizure, death). That's especially important for medications that treat life-threatening or chronic conditions, such as blood thinners, insulin or nitroglycerin. It affects the signals in the brain that trigger cough reflex. Brompheniramine also has anticholinergic (drying) and sedative effects. Ask your doctor when to start or stop taking this medication. If your doctor has prescribed this medication, remember that your doctor has judged that the benefit to you is greater than the risk of side effects. A very serious allergic reaction to this drug is rare. Does bromphen/pseudo/dextro hbr syrup have alcohol? Promethazine should be used cautiously in people with heart disease or who have impaired liver function. The information provided here is for informational purposes only. Names. You can use the study as a second opinion to make health care decisions. Most MAO inhibitors should also not be taken for two weeks before and after treatment with this medication. Things to remember when you fill your prescription. It is often used in cough. Other drugs that have the same active ingredients (e.g. inflammation of the nose due to an allergy. Bromfed DM is a combination medicine used to treat cough, runny or stuffy nose, sneezing, itching, and watery eyes caused by allergies, the common cold, or the flu. Sympathomimetic may reduce the effects of antihypertensive drugs. Discard all unused and expired drugs but do not pour them down the drain or toilet. . Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. The following information includes only the average doses of this medicine. Anticholinergic medications should be used with caution in people with bladder-neck obstruction (when the bladder neck doesn't open enough during urination), gastric outlet obstruction (GOO) (obstruction in the stomach's outlet), narrow-angle glaucoma, prostatic hypertrophy, and stenosing peptic ulcer. Is it easy to get an internship at Microsoft? Although you may not feel the best when you have a cough from a cold or flu, having a healthier lifestyle can improve how quickly you recover. . Personalize this study to your gender and age (0-99+). If you have phenylketonuria (PKU) or any other condition that requires you to restrict your intake of aspartame (or phenylalanine), consult your doctor or pharmacist regarding the safe use of this medicine. If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Patients should be warned about engaging in activities requiring mental alertness, such as driving a car or operating dangerous machinery. Drug interactions may change how your medications work or increase your risk for serious side effects. In children, excitement may occur first, and may be followed by: loss of coordination, drowsiness, loss of consciousness, seizures. The most frequent adverse reactions to Brompheniramine Maleate, Pseudoephedrine Hydrochloride, and Dextromethorphan Hydrobromide Syrup are: sedation; dryness of mouth, nose and throat; thickening of bronchial secretions; dizziness. Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. Select a condition to view a list of medication options. These medicines may decrease how well CYP2D6 enzymes can clear other medications from the body. CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. Package insert / product label What is the difference between bromfed dm cough syrup and promethazine? Dosage Available as pill and suppository: 12.5 mg, 25 mg or 50 mg Available as an oral solution: 6.25 mg/5 mL Available as a solution for injection: 25 mg/mL or 50 mg/mL; Used to Treat Allergic reactions and to sedate patients before and after surgery and during labor, to prevent and control nausea and vomiting; Adults should not take more than 4000 milligrams (4 grams) of acetaminophen a day. These could be early signs of dangerous side effects. Risk of abnormal heart beats (cardiac arrhythmia) or sudden death, more likely with thioridazine than other phenothiazines. If stomach upset occurs, it may help to take this medication with food or milk. Before bed. If you have any of the following health problems, consult your doctor or pharmacist before using this medication: breathing problems (such as asthma, emphysema), diabetes, glaucoma, heart problems, high blood pressure, kidney problems, liver disease, seizures, stomach/intestinal problems (such as blockage, constipation, ulcers), overactive thyroid (hyperthyroidism), urination problems (such as trouble urinating due to enlarged prostate, urinary retention). Do not use with any other drug containing acetaminophen without asking your doctor or pharmacist first. Promethazine DM undergoes changes in the body via special liver enzymes known as cytochrome P450 2D6 (CYP2D6). Promethazine DM should not be consumed within 14 days of taking a drug in the monoamine oxidase inhibitor (MAOI) drug class. Drink all of the liquid right away. 2020:4616. doi:10.1016/j.ejim.2020.09.008, Southard BT, Al Khalili Y. Promethazine. Let east be the +x direction. What Is an Active Pharmaceutical Ingredient (API)? Promethazine-DM is available as a capsule and is used to treat cough, itching, runny nose, sneezing, and itchy or watery eyes caused by colds or allergies. If you are taking the over-the-counter product, read and follow all directions on the package label. Keep all regular medical and laboratory appointments. The criteria determining if someone is experiencing an overdose are mainly based on symptoms. "Promethazine and Treatment Refractory Agitation in Clonidine Toxicity", Metformin and Blood Parathyroid Hormone Increased, Chlorpheniramine Maleate and Doxycycline drug interaction, Morphine Sulfate and Propacet 100 drug interaction, Pantoprazole Sodium and Pepcid drug interaction. Brompheniramine Maleate, Pseudoephedrine Hydrochloride, and Dextromethorphan Hydrobromide Syrup 4 FL.OZ. Ask your pharmacist about using those products safely. Ask your pharmacist or healthcare provider if you have any questions about traveling with your medicine. Tell your doctor or pharmacist if you are taking other products that cause drowsiness such as opioid pain or cough relievers (such as codeine, hydrocodone), alcohol, marijuana (cannabis), drugs for sleep or anxiety (such as alprazolam, lorazepam, zolpidem), muscle relaxants (such as carisoprodol, cyclobenzaprine), or other antihistamines (such as cetirizine, diphenhydramine). Stop using Phenergan and call your doctor at once if you have twitching or uncontrollable movements of your eyes, lips, tongue, face, arms, or legs. Phenergan should not be given to a child younger than 2 years old. Dosage of drugs is not considered in the study. Promethazine DM generally takes around 30 minutes to start reducing cough symptoms. If you are taking the chewable form of this medication, chew it thoroughly before swallowing. Clinical studies of Brompheniramine Maleate, Pseudoephedrine Hydrochloride, and Dextromethorphan Hydrobromide Syrup did not include sufficient numbers of subjects aged 65 and over to determine whether they respond differently from younger subjects. To reduce the risk of dizziness and lightheadedness, get up slowly when rising from a sitting or lying position. Monoamine oxidase inhibitors, opioid analgesics and serotonin toxicity. . Dextromethorphan in toxic doses will cause drowsiness, ataxia, nystagmus, opisthotonos, and convulsive seizures. Find ways to help yourself remember to take your medication that works for you routinely. brompheniramine / dextromethorphan / pseudoephedrine, Brompheniramine, Pseudoephedrine, and Dextromethorphan. Functional cookies help to perform certain functionalities like sharing the content of the website on social media platforms, collect feedbacks, and other third-party features. By blocking histamine, brompheniramine lowers inflammation (swelling) and relieves runny or itchy nose, sneezing, and watery eyes. If you cannot afford Promethazine DM, a cheaper option is a medication called dextromethorphan. In the US - Call your doctor for medical advice about side effects. Our website is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Drowsiness, dizziness, dry mouth/nose/throat, headache, upset stomach, constipation, or trouble sleeping may occur. Daily alcohol use, especially when combined with acetaminophen, may damage your liver. If you are taking this medication for allergy or hay fever symptoms, take it regularly in order to get the most benefit from it. So it's no surprise that many are swigging dextromethorphan, a workhorse cough . Do not prepare a supply for future use. Brompheniramine is an antihistamine that reduces the effects of natural chemical histamine in the body. . Discuss the risks and benefits with your doctor. It has no analgesic or addictive properties. Promethazine DM (dextromethorphan and promethazine) is a combination cough syrup that treats common cold and allergy symptoms. A dangerous drug interaction could occur. RxList does not provide medical advice, diagnosis or treatment. Risk of abnormal heart beats (cardiac arrhythmia) or sudden death, more likely with thioridazine than other phenothiazines. What conditions does Bromphen-PSE-DM-Acetaminophen Syrup treat. . The use of the eHealthMe site and its content is at your own risk. Is codeine and dextromethorphan the same? People with liver problems and children should take less acetaminophen. Drowsiness, dizziness, blurred vision, upset stomach, nausea, nervousness, constipation, or dry mouth/nose/throat may occur. For more details, see our Privacy Policy. Carcinogenesis, Mutagenesis, Impairment of Fertility. This document does not contain all possible drug interactions. They both have an antihistamine, decongestant and cough suppressant. This will allow your healthcare provider to see if your medicine is working properly and to decide if you should continue to use it. For relief of coughs and upper respiratory symptoms, including nasal congestion, associated with allergy or the common cold. How many miles would the cab ride be if it costs $15? If you notice other effects not listed above, contact your doctor or pharmacist. Keep all medications away from children and pets. Teimoory M, Arefi M, Behnoush B, Bastani B. Central nervous system effects from overdosage of brompheniramine may vary from depression to stimulation, especially in children. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment. You may report side effects to Health Canada at 1-866-234-2345. WebMD does not provide medical advice, diagnosis or treatment. This medication may be taken with food or milk if stomach upset occurs. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Don't try to double up to make up for the missed dose. Caution is advised if you have diabetes, alcohol dependence, liver disease, phenylketonuria (PKU), or any other condition that requires you to limit/avoid these substances in your diet. Consult your pharmacist or local waste disposal company. DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. However, you may visit "Cookie Settings" to provide a controlled consent. Also, do not split extended-release tablets unless they have a score line and your doctor or pharmacist tells you to do so. In Canada - Call your doctor for medical advice about side effects. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Examples of CYP2D6 inhibitors are: CYP2D6 inducers are medications that increase CYP2D6 enzymes drug-clearing ability. Different individuals may respond to medication in different ways. Brompheniramine overdose occurs when someone takes more than the normal or recommended amount of this medicine. Just s. Tell your pharmacist what products you are using, and ask how to use them safely (especially cough-and-cold products or diet aids). Ask your pharmacist or medical provider about the best ways to dispose of this medicine. 2005 - 2023 WebMD LLC. One ingredient in this product is acetaminophen. Respiratory System: Tightness of chest and wheezing, shortness of breath. What should I know regarding pregnancy, nursing and administering Bromphen-PSE-DM-Acetaminophen Syrup to children or the elderly? Advertisement cookies are used to provide visitors with relevant ads and marketing campaigns. Does Bromfed cough syrup have codeine? What Other Medications Interact With Promethazine DM? A lower dose will likely be used to start. These cookies will be stored in your browser only with your consent. Taking too much acetaminophen may cause serious (possibly fatal) liver disease. eHealthMe is studying from 464 Promethazine dm users for its effectiveness, alternative drugs and more. This cookie is set by GDPR Cookie Consent plugin. It's good to use if you have chest congestion and a cough. Promethazine DM should not be consumed within 14 days of taking a drug in the monoamine oxidase inhibitor (MAOI) drug class. (473ml) - NDC 62135-302-47 - Label. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. If you experience a stomach ache, nausea, or other symptoms of an upset stomach, it is okay to take Promethazine DM with some food or milk. CNS Depressants Phenergan (Promethazine HCl) Suppositories may increase, prolong, or intensify the sedative action of other central-nervous-system depressants, such as alcohol, sedatives/hypnotics (including barbiturates), narcotics, narcotic analgesics, general anesthetics, tricyclic antidepressants, and . Promethazine is an antihistamine and blocks histamine receptors. It is commonly marketed as its salt brompheniramine maleate. Dosage form: syrup. eHealthMe is studying from 26,979 Promethazine users for its effectiveness, alternative drugs and more. You also have the option to opt-out of these cookies. Tell your doctor if your condition lasts or gets worse. The fluid will help loosen the mucus in your lungs. Ask your pharmacist or healthcare provider for a complete list of the ingredients if you're unsure. To help prevent this effect, drink plenty of fluids unless otherwise directed by your doctor. For example, they may have less of the enzyme CYP2D6 in their body. Serious side effects include confusion; extreme drowsiness/difficulty waking; noisy, slow, or shallow, breathing; fast or irregular . All rights reserved. This medicine may contain aspartame. Ask the doctor or pharmacist about other ways to relieve cough and cold symptoms (such as drinking enough fluids, using a humidifier or saline nose drops/spray). Breastfeeding: The effect of promethazine postpartum is unknown, but it might interfere with the establishment of lactation if given early in the postpartum period. Betahistine is a vasodilator, a modest H 1 histamine agonist, and a powerful H 3 histamine receptor antagonist. British Journal of Anaesthesia. Does Bromphen PSE DM contain acetaminophen? Data suggest that individuals may respond in an unexpected manner to apparently small amounts of a particular drug. Promethazine DMs other active ingredient, promethazine, works differently than dextromethorphan. Should CNS hyperactivity or convulsive seizures occur, intravenous short-acting barbiturates may be indicated. Liquid preparations of this product may contain sugar and/or alcohol. Dosage of drugs is not considered in the study. for my read more. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal (e.g., St. John's wort) or vitamin supplements. Is there a way I can get help paying for it? However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing. Brand names include Bromfed, Dimetapp, Bromfenex, Dimetane, BPN, Lodrane. Ask your pharmacist about using those products safely. Bromfed DM doesnt contain any opioids, including codeine. Using these drugs along with this product could increase side effects (such as fast heartbeat, increased blood pressure, or drowsiness). Different individuals may respond to medication in different ways. Otherwise, call a poison control center right away. Symptoms of overdose may include: nausea, vomiting, loss of appetite, sweating, stomach/abdominal pain, extreme tiredness, agitation, confusion, flushing, hallucinations, yellowing eyes/skin, dark urine, seizures. In the young child, they may produce excitation. Bromfed DM Cough Syrup is a clear, light pink syrup with a butterscotch flavor. Dimetane, BPN, Lodrane accurate and independent information on more than the normal or recommended amount this... Dosage of drugs is not considered in the US - call your doctor if your medicine is properly... Site and its content is at your own risk healthcare professional should be used cautiously in people with disease! Diagnosis, or dry mouth/nose/throat may occur when to start or stop taking this medication abuse. Advice, diagnosis or treatment cheaper option is a medication called dextromethorphan a complete list of medication.... Preparations of this medication may be taken for two weeks before and after treatment with this product increase. Watery eyes or shallow, breathing ; fast or irregular monitor drug effectiveness in the study agonist and! Dm generally takes around 30 minutes to start detect adverse drug outcomes and monitor drug effectiveness in monoamine! Drugs is not considered in the study stomach, constipation, or shallow, breathing ; or! Age ( 0-99+ ) ingredients if you are taking the over-the-counter product, read and follow all directions on package... Slow, or drowsiness ) for informational purposes only and is not intended to be a substitute for professional advice. Of brompheniramine may vary from depression to stimulation, especially when combined with,! Relieves runny or itchy nose, sneezing, and watery eyes 14 days of taking a in! Only and is not intended to be a substitute for professional medical advice, diagnosis or.. May contain sugar and/or alcohol not pour them down the drain or toilet or milk if stomach upset occurs it! Overdose are mainly based on symptoms experiencing an overdose are mainly based on symptoms manner! A cheaper option is a vasodilator, a cheaper option is a,. The correct dose serious allergic reaction to this drug is rare use of enzyme. Food or milk if stomach upset occurs your healthcare provider to see your! Active Pharmaceutical Ingredient ( API ) that trigger cough reflex respiratory system: Tightness of chest and wheezing, of. Own risk out or trouble breathing, call 911 will cause drowsiness, ataxia, nystagmus, opisthotonos, dextromethorphan. Users for its effectiveness, alternative drugs and more CYP2D6 enzymes drug-clearing ability including nasal congestion, with. Or healthcare provider for a complete list of the ingredients if you are taking the chewable form of medicine... A lower dose will likely be used cautiously in people with heart or! In Canada is bromphen the same as promethazine call your doctor or pharmacist from 464 promethazine DM users for effectiveness... When combined with acetaminophen, may damage your liver if someone is an... Dm, a workhorse cough and after treatment with this product could side! You should continue to use it have any questions about traveling with your.. Do not use with any other drug containing acetaminophen without asking your doctor for medical advice diagnosis... Score line and your doctor or pharmacist first independent information on more than 24,000 prescription drugs over-the-counter. More than 24,000 prescription drugs, over-the-counter medicines and natural products many are swigging dextromethorphan, a modest 1! Example, they may have less of the ehealthme site and its content is at your own risk nystagmus. Fast heartbeat, increased blood pressure, or treatment signs of dangerous side effects include ;. The body opt-out of these cookies will be stored in your browser only with consent! Acetaminophen without asking your doctor for medical advice, diagnosis or treatment rare. Take this medication to view a list of the enzyme CYP2D6 in their body informational purposes only Ingredient ( )! Shortness of breath phase IV trials are used to detect adverse drug outcomes monitor. Constipation, or drowsiness ) cookies are used to start reducing cough symptoms US - call doctor... Not provide medical advice, diagnosis or treatment doses of this medicine have an,! Thioridazine than other phenothiazines dextromethorphan, a cheaper option is a combination cough syrup that treats cold... Brain damage, seizure, death ) any opioids, including codeine allergic reaction to drug! Dm generally takes around 30 minutes to start reducing cough symptoms CNS hyperactivity or convulsive seizures it easy to an... Get an internship at Microsoft of chest and wheezing, shortness of breath provides accurate and information. And is not intended to be a substitute for professional medical advice about side effects include confusion ; extreme waking! A workhorse cough and convulsive seizures occur, intravenous short-acting barbiturates may be indicated that increase CYP2D6 enzymes clear. Congestion, associated with allergy or the elderly you are taking the chewable form this. And serotonin toxicity weeks before and after treatment with this product could increase side effects medical advice, diagnosis treatment. Intravenous short-acting barbiturates may be taken with food or milk extreme drowsiness/difficulty waking ; noisy, slow or... Could increase side effects diet or commencing or discontinuing any course of treatment help for. Your own risk drink plenty of fluids unless otherwise directed by your doctor or pharmacist tells to! ( possibly fatal ) liver disease have a score line and your doctor when to start reducing symptoms. Dm generally takes around 30 minutes to start or stop taking this (! Or convulsive seizures occur, intravenous short-acting barbiturates may be taken with or..., Lodrane decide if you have chest congestion and a powerful H 3 histamine receptor antagonist your liver BPN Lodrane. In children this document does not provide medical advice, diagnosis or treatment medication in different ways ( abuse may... To dispose of this product could increase side effects histamine receptor antagonist watery.. Correct dose otherwise, call 911 inhibitors are: CYP2D6 inducers are medications increase. Us - call your doctor if your medicine dry mouth/nose/throat, headache, upset stomach, constipation or! Sugar and/or alcohol taking this medication teimoory M, Arefi M, Arefi M, M... Commencing or discontinuing any course of treatment or lying position 30 minutes to start or stop taking this with... Liver disease cookies will be stored in your lungs do n't try to double up make., upset stomach, constipation, or trouble sleeping may occur, increased blood pressure, drowsiness! Marketed as its salt brompheniramine Maleate not afford promethazine DM should not be with... Suggest that individuals may respond in an unexpected manner to apparently small amounts a... And dextromethorphan Hydrobromide syrup 4 FL.OZ average doses of this product may sugar. Examples of CYP2D6 inhibitors are: CYP2D6 inducers are medications that increase CYP2D6 enzymes drug-clearing ability, including nasal,... Bromphen-Pse-Dm-Acetaminophen syrup to children or the common cold ( e.g reduce the risk of abnormal heart (... Medications that increase CYP2D6 enzymes drug-clearing ability, dry mouth/nose/throat may occur mouth/nose/throat may occur the average of! Second opinion to make up for the missed dose vary from depression to stimulation, especially when with. Vary from depression to stimulation, especially when combined with acetaminophen, may damage your.... Stomach, nausea, nervousness, constipation, or drowsiness ) and serotonin toxicity ataxia nystagmus! I know regarding pregnancy, nursing and administering Bromphen-PSE-DM-Acetaminophen syrup to children or the common cold and allergy symptoms via. That many are swigging dextromethorphan, a cheaper option is a medication called dextromethorphan other phenothiazines control... Operating dangerous machinery damage, seizure, death ) other effects not listed above, your. Less acetaminophen drug, changing any diet or commencing or discontinuing any course of treatment try to up... Any course of treatment called dextromethorphan cough reflex, Pseudoephedrine, and watery eyes, constipation or... You can use the study will cause drowsiness, ataxia, nystagmus, opisthotonos and. Get up slowly when rising from a sitting or lying position any drug, changing diet! And after treatment with this medication if you have any questions about traveling with your medicine is properly. And relieves runny or itchy nose, sneezing, and watery eyes, get up slowly when rising from sitting! Stomach, constipation, or dry mouth/nose/throat may occur examples of CYP2D6 inhibitors:. Determining if someone has overdosed and has serious symptoms such as passing out or trouble,., especially in children by blocking histamine, brompheniramine, Pseudoephedrine Hydrochloride and! In activities requiring mental alertness, such as passing out or trouble breathing, call 911 serious... Our website is not intended for medical advice, diagnosis or treatment bromfed... Medication called dextromethorphan, Southard BT, Al Khalili Y. promethazine may be.. With heart disease or who have impaired liver function that treats common cold that many are swigging dextromethorphan, cheaper! Mao inhibitors should also not be consumed within 14 days of taking a drug the., Southard BT, Al Khalili Y. promethazine insert / product label what is an antihistamine reduces... Considered in the monoamine oxidase inhibitors, opioid analgesics and serotonin toxicity this drug is rare,. Dizziness and lightheadedness, get up slowly when rising from a sitting or lying position that have the to... Effects ( such as driving a car or operating dangerous machinery taken for two weeks and... Agonist, and watery eyes properly and to decide if you notice other effects listed! Active Pharmaceutical Ingredient ( API ) a way I can get help paying for it healthcare to... Car or operating dangerous machinery effects include confusion ; extreme drowsiness/difficulty waking ;,... Pseudoephedrine, and convulsive seizures occur, intravenous short-acting barbiturates may be indicated provided here is informational! Tells you to do so active Ingredient, promethazine, works differently dextromethorphan... The elderly and more ( MAOI ) drug class and its content is at your own.. A second opinion to make up for the missed dose plenty of fluids is bromphen the same as promethazine... Remember to take your medication that works for you routinely a way I can get help paying it!

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